Last Updated: 2014-02-26
Refers to the clinical syndrome of heart failure with symptoms of pulmonary and peripheral congestion in the presence of normal left-ventricular systolic function and increased diastolic filling pressures.
Accounts for about 50% of all patients with heart failure, and carries a similar prognosis.
The most common risk factors are advanced age, female gender, hypertension, obesity, chronic kidney disease, diabetes mellitus, and coronary artery disease.
Patients may present with acute decompensated heart failure and are generally managed with diuresis, blood pressure control, and treatment of ischemia and tachyarrhythmia, when present.
No therapy has been shown to improve survival in randomized control trials. Risk factor modification is still the cornerstone of long-term management.
Stage I diastolic dysfunction: impaired relaxation
From the collection of Dr Del Rosario
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