Chronic inflammatory skin disease characterized by extensive erythematous, circumscribed scaly papules, and plaques.
Runs a variable course and seldom completely subsides. Severity is aggravated by genetic, infectious, emotional, and environmental factors.
Lesions are red, inflamed, silvery-white scaly, and circumscribed papules and plaques on elbows, knees, extensor limbs, and scalp. Psoriatic nails have a pitted surface and/or hypertrophic (subungual) changes.
Skin biopsy may aid diagnosis.
Mild and limited psoriasis is treated with topical emollients, corticosteroids, tar preparations, vitamin D analogs, and anthralin.
Moderate to severe and/or extensive psoriasis may require phototherapy, oral retinoids, methotrexate, biological agents, or cyclosporine.
Plaque psoriasis on legs
From the collection of Professor Tsu-Yi Chuang, MD, MPH, FAAD
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