Inflammatory bowel disease that may involve the entire gastrointestinal tract.
Common presenting symptoms include chronic diarrhea, weight loss, and right lower quadrant abdominal pain mimicking acute appendicitis.
Diagnosis confirmed by colonoscopy with ileoscopy and tissue biopsy.
The overall treatment goals are to induce and maintain remission plus prevent relapse or recurrence.
Complications include extraintestinal involvement, intestinal obstruction, abscess formation, sinuses, and fistulae.
Significant inflammation in the colonic wall, widening of submucosa, and dense lymphoid aggregates in the submucosa
Provided by Drs Wissam Bleibel, Bishal Mainali, Chandrashekhar Thukral, and Mark A. Peppercorn, the previous authors of this monograph