Last Updated: 2013-03-11
Demyelinating polyneuropathy classified according to symptoms and divided into axonal and demyelinating forms.
Two-thirds have a history of gastroenteritis or influenza-like illness weeks before onset of neurologic symptoms.
Up to 30% will develop respiratory muscle weakness requiring ventilation.
Neurophysiology is confirmatory and is abnormal in 85% of patients, even early in the disease.
LP is useful, and the classic finding is elevated protein with normal cell count (albuminocytologic dissociation).
Treatment combines supportive and disease-modifying therapy (plasma exchange or high-dose immunoglobulin).
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