Last Updated: 2013-04-25
Incidence increasing along with number of patients who are overweight or obese.
Associated with increased cardiovascular risk.
May cause acute pancreatitis when fasting levels >500 mg/dL.
Treatment includes lifestyle modification for all patients.
Statins are generally first-line pharmacotherapy in patients with triglycerides <500 mg/dL in the presence of ≥2 cardiac risk factors.
Fibric acid derivatives, fish oils, and/or nicotinic acid may be added to statins, to achieve targets, in patients with triglycerides <500 mg/dL, or as first-line therapy in those with triglycerides ≥500 mg/dL.
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