Last Updated: 2013-04-03
May present with symptomatic hypocalcemia, perioral and digital paresthesias, positive Chvostek and Trousseau signs. If the condition does not cause clinically significant hypocalcemia, hypoparathyroidism may be entirely asymptomatic.
Majority of cases are iatrogenic, following surgery; other causes include congenital, infiltrating disease, PTH suppression, PTH resistance, HIV/AIDS.
Initial laboratory tests typically reveal low calcium and low or inappropriately normal immunoreactive PTH, and may reveal low magnesium and low vitamin D.
Urgent calcium, magnesium, and vitamin D replacement is indicated if symptoms are present.
Nail dystrophy due to hypocalcemia
Nijjer S, Ghosh AK, Dubrey SW. Hypocalcaemia, long QT interval and atrial arrhythmias. BMJ Case Reports 2010 [doi:10.1136/bcr.08.2009.2216]. Copyright © 2011 by the BMJ Publishing Group Ltd.
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