Last Updated: 2013-12-06
Acute onset of severe joint pain.
Swelling, effusion, warmth, erythema and/or tenderness of the involved joint(s).
Arthrocentesis with synovial fluid analysis shows strongly negative birefringent needle-shaped crystals under polarized light.
NSAIDs, colchicine, or corticosteroids are used to treat acute disease.
Allopurinol, febuxostat, or probenecid are used as uric acid-lowering drugs when long-term prevention of crystal deposition is indicated.
Complications include joint destruction, kidney disease, and urolithiasis.
Chronic tophaceous gout showing nodules in periarticular structures and arthritis
Adapted from BMJ Case Reports 2009 [doi:10.1136/bcr.03.2009.1668] Copyright © 2009 by the BMJ Group Ltd
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