Last Updated: 2013-03-21
Clinical syndrome usually caused by Epstein Barr virus (EBV).
Characterized by fever, pharyngitis, lymphadenopathy, and atypical lymphocytosis, in older children and young adults.
Often subclinical in young children.
Positive heterophile antibody test and serologic test for antibodies against EBV are usually diagnostic.
Rare but potentially life-threatening complications include severe upper airway obstruction, splenic rupture, fulminant hepatitis, encephalitis, severe thrombocytopenia, and hemolytic anemia.
Treatment is usually symptomatic.
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