Last Updated: 2013-10-09
An acute inflammation of the oral mucosa following systemic chemotherapy and/or radiation to fields involving the oral cavity.
Clinical presentation ranges from a general erythematous stomatitis to erosive lesions and overt ulceration. Lesions are often very painful, compromise nutrition and oral hygiene, and increase risk of local and systemic infection.
If severe, may warrant an undesirable chemotherapy dose-reduction and/or a break in radiation therapy.
Treatment is symptomatic and includes oral hygiene and pain control.
Preventive treatments include palifermin and use of ice-chips during chemotherapy infusion therapy.
Mucositis: dorsolateral tongue
From the teaching collection of Rajesh V. Lalla, DDS, PhD, CCRP, DABOM
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