A leading cause of morbidity and mortality.
Approximately 85% of strokes are ischemic, caused by vascular occlusion.
A clinical emergency: timely diagnosis, triage, and intervention can improve outcome.
Care of patients in dedicated stroke units results in improved survival and function.
Intravenous tissue plasminogen activator is given within 4.5 hours of stroke onset.
Intra-arterial reperfusion therapies, using either intra-arterial thrombolysis or clot retrieval devices, are used by experienced centers in select cases up to 8 hours from symptom onset.
(A) T2-weighted MRI image showing hyperintense signal representing prolonged T2. Shows abnormal T2 of 153.38 ms on the left, compared with the normal contralateral side (96 ms). Note that the lesion is located on the ascending frontal gyrus. (B) Gradient echo images detect hemosiderin compounds due to magnetic susceptibility of iron. In this case the result is negative
From the personal collection of Eric E. Smith