Select a medication above to begin.
Black Box Warnings .
may occur in anticoagulated pts receiving neuraxial anesthesia or spinal puncture; hematoma may result in long-term or permanent paralysis; incr. hematoma risk if indwelling epidural catheter use, concomitant use of drugs affecting hemostasis incl. NSAIDs, platelet inhibitors or other anticoagulants, traumatic or repeated epidural/spinal puncture hx, spinal deformity, or spinal surgery hx; weigh risk/benefit before neuraxial intervention in anticoagulated pts or planned anticoagulation for thromboprophylaxis; while optimal timing to minimize risk is unknown, delay spinal catheter placement or removal >12h after prophylactic doses and >24h after tx doses; consider delaying post-procedural dose >4h after catheter removal; for pts w/ CrCl <30, consider delaying spinal catheter placement or removal >24h after prophylactic doses and >48h after tx doses; monitor s/sx neurologic impairment frequently, treat urgently if needed