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Adult Dosing .
Dosage forms: 0.1% foam
- [apply qhs]
- Info: do not apply to eczematous skin
Peds Dosing .
- Dosage forms: 0.1% foam
- [>12 yo]
- Dose: apply qhs; Info: do not apply to eczematous skin
- hypersens. to drug/class/compon.
- caution if photosensitizing drug use
- caution if sunburn
- caution if skin CA hx
- caution if skin CA family hx
Drug Interactions .
- skin irritant/drying agent
- adapalene topical
- benzoyl peroxide topical
- sulfur topical
- tretinoin topical
- methoxsalen topical
Adverse Reactions .
- skin irritation
- contact dermatitis
Lactation: Safety Unknown
pregnancy test <2wk before tx start
Metabolism: skin, liver; CYP450: unknown; Info: prodrug converted to tazarotenic acid; minimal systemic absorption
Excretion: urine, feces; Half-life: 18-21.7h
Subclass: Acne, Topical
Mechanism of Action
exact mechanism of action unknown; binds to retinoic acid receptors, modulating keratinocyte hyperproliferation and differentiation; exerts anti-inflammatory effects (retinoid)
Manufacturer: Stiefel Laboratories, Inc.
Approximate Retail Price
This information is currently not available for this drug.
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