Adult Dosing .
Dosage forms: 0.5% sol
- [1 gtt in eye(s) q2h up to 8x/day x1 day, then 1 gtt bid-qid x6 days]
Peds Dosing .
- Dosage forms: 0.5% sol
- [>1 yo]
- Dose: 1 gtt in eye(s) q2h up to 8x/day x1 day, then 1 gtt bid-qid x6 days
- hypersens. to drug/class/compon.
Drug Interactions .
No significant interactions known or found for this drug. Caution always advised with multiple medications.
Adverse Reactions .
- conjunctival hemorrhage
- superinfection (prolonged use)
- hypersensitivity rxn
- conjunctival irritation
- ocular irritation
- ocular pain
- dry eyes
- ocular discharge
- lacrimation incr.
- papillary conjunctivitis
- visual acuity changes
Lactation: Safety Unknown
no routine tests recommended
Look/Sound-Alike Drug Names
gatifloxacin confused with: levofloxacin; moxifloxacin
Metabolism: minimal; CYP450: none; Info: minimal to no systemic absorption
Excretion: urine primarily (primarily unchanged); Half-life 7-14h
Subclass: Antibacterials, Ophthalmic
Mechanism of Action
bactericidal; inhibits DNA gyrase and topoisomerase IV (fluoroquinolone)
Approximate Retail Price
This information is currently not available for this drug.
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