Adult Dosing .
Dosage forms: 800 mg; 0.8,2.4 g pwdr pkt
- [dosing clarification]
- Info: give 3h before or 1h after other oral drugs
hyperphosphatemia, dialysis pts
- [individualize dose PO tid]
- Start: 800 mg PO tid if PO4 5.6-7.4 mg/dL or 1600 mg PO tid if PO4 >7.5 mg/dL; Max: 14 g/day; Info: may adjust by 800 mg/dose q2wk to maintain PO4 3.5-5.5 mg/dL; give w/ meals
- [no adjustment]
- [not defined]
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.
- hypersens. to drug/class/compon.
- GI obstruction
- caution if dysphagia (PO tab form)
- caution if GI motility disorder
- caution if constipation, severe
- caution if major GI tract surgery
Drug Interactions .
- anion exchange resin/polymer
- mycophenolate mofetil
- mycophenolic acid
Adverse Reactions .
- fecal impaction
- intestinal obstruction
- intestinal perforation
- dysphagia (PO tab form)
- abdominal pain
Lactation: Safety Unknown
Cl, bicarbonate; folic acid; 25-hydroxycalciferol; PT/aPTT
Metabolism: none; CYP450: none; Info: no systemic absorption
Excretion: feces; Half-life: unknown
Subclass: Phosphate Binders
Mechanism of Action
binds intestinal phosphate, lowering serum phosphorus (cationic polymer)
Approximate Retail Price
This information is currently not available for this drug.
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