Adult Dosing .
Dosage forms: 0.5% sol
- [1-2 gtt in eye(s) q2h while awake x2 days, then q4h while awake x5 days]
- Max: 8 doses/day on days 1-2; 4 doses/day on days 3-7
Peds Dosing .
- Dosage forms: 0.5% sol
- [>1 yo]
- Dose: 1-2 gtt in eye(s) q2h while awake x2 days, then q4h while awake x5 days; Max: 8 doses/day on days 1-2; 4 doses/day on days 3-7
- hypersens. to drug/class/compon.
Drug Interactions .
No significant interactions known or found for this drug. Caution always advised with multiple medications.
Adverse Reactions .
- vision decr., transient
- foreign body sensation
- ocular burning
- ocular discomfort
Lactation: Safety Unknown
no routine tests recommended
Metabolism: minimal; CYP450: unknown; Info: minimal systemic absorption
Excretion: urine primarily (87% unchanged); Half-life: 6-8h; Info: partial active tubular secretion
Subclass: Antibacterials, Ophthalmic
Mechanism of Action
bactericidal; inhibits DNA gyrase and topoisomerase IV (fluoroquinolone)
Approximate Retail Price
- 0.5 % (1 eye dropper, 5mL): $83.72
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