Adult Dosing .
Dosage forms: 2% crm
- [pregnant pts]
- Dose: 1 applicatorful PV qhs x7 days
- [non-pregnant pts]
- Dose: 1 applicatorful PV qhs x3 or 7 days
- [not defined]
- [not defined]
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.
- hypersens. to drug/class/compon.
- inflammatory bowel dz
- abx-assoc. colitis hx
Drug Interactions .
- progesterone vaginal (hormone replacement)
Adverse Reactions .
- pseudomembranous colitis
- vaginal discharge
- vulvovaginal irritation
- candidiasis, vulvovaginal
- abdominal cramps
- vaginal pain
Lactation: Safety Unknown
no routine tests recommended
Look/Sound-Alike Drug Names
clindamycin confused with: clarithromycin; Clinoril; gentamicin; vancomycin
Metabolism: liver; CYP450: unknown; Info: active metabolites; 30% systemic absorption
Excretion: urine, feces; Half-life: 11h; Info: half-life limited by absorption rate
Subclass: Antimicrobials, Vaginal
Mechanism of Action
bacteriostatic or bactericidal, depending on susceptibility and concentration; binds to 50S ribosomal subunit, inhibiting protein synthesis (lincosamide)
Approximate Retail Price
This information is currently not available for this drug.
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