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Zaltrap
ziv-aflibercept
Adult Dosing .
Dosage forms: INJ
Special Note
- [uses, dosing may vary]
- Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments; D/C >4wk before elective surgery, restart >4wk after major surgery when wound fully healed
colorectal CA, refractory metastatic
- [4 mg/kg/dose IV x1 on day 1 of 14-day cycle]
- Info: for pts w/ dz resistant to or progressed following an oxaliplatin-containing regimen; part of multi-drug chemo regimen
renal dosing
- [see below]
- renal impairment: no adjustment
- HD/PD: not defined
hepatic dosing
- [see below]
- bilirubin 1.1-3x ULN: no adjustment; bilirubin >3x ULN: not defined
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.