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Thymoglobulin
anti-thymocyte globulin (rabbit)
Black Box Warnings .
Appropriate Use
use only by physicians experienced in immunosuppress. tx for mgmt of renal transplant pts
Adult Dosing .
Dosage forms: INJ
kidney transplant rejection, acute
- [prophylaxis]
- Dose: 1.5 mg/kg/dose IV qd x4-7 days; Start: prior to reperfusion of donor kidney; Info: premed w/ corticosteroids, antipyretic, and/or antihistamine 1h prior to each dose; decr. dose 50% if WBC 2000-3000 or Plt 50,000-75,000; consider D/C if WBC <2000 or Plt <50,000
- [treatment]
- Dose: 1.5 mg/kg/dose IV qd x7-14 days; Info: premed w/ corticosteroids, antipyretic, and/or antihistamine 1h prior to each dose; decr. dose 50% if WBC 2000-3000 or Plt 50,000-75,000; consider D/C if WBC <2000 or Plt <50,000
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.