Select a medication above to begin.
glycopyrrolate
generic
Adult Dosing .
Dosage forms: TAB: 1 mg, 2 mg; INJ (pre-filled syringe): 0.2 mg per mL; INJ (vial): 0.2 mg per mL
anesthesia adjunct
- [preop]
- Dose: 0.004 mg/kg/dose IM x1; Start: 30-60min before anesthesia; Info: for reduction of secretions
- [intraop]
- Dose: 0.1 mg IV q2-3min prn; Info: for reversal of bradycardia, vagal reflexes
neuromuscular blockade reversal adjunct
- [0.2 mg IV for each 1 mg neostigmine or 5 mg pyridostigmine dose]
- Info: for reversal of muscarinic effects of cholinergic agents
PUD, adjunct tx
- [PO route]
- Dose: 1-2 mg PO bid-tid; Start: 1 mg PO tid; Max: 8 mg/day
- [parenteral route]
- Dose: 0.1-0.2 mg IM/IV tid-qid; Max: 0.8 mg/day; Info: space doses 4h apart
antisialogogue (off-label)
- [PO route]
- Dose: 1-2 mg PO bid-tid prn; Max: 8 mg/day; Info: injectable product may be given PO
- [parenteral route]
- Dose: 0.1-0.2 mg SC/IM/IV q4-8h prn; Max: 0.8 mg/day
hyperhidrosis (off-label)
- [1-2 mg PO bid-tid prn]
- Start: 1 mg PO bid; Max: 8 mg/day
renal dosing
- [PO route]
- renal impairment: not defined, caution advised
- HD/PD: not defined, caution advised
- [parenteral route]
- renal failure: consider decr. usual dose
- HD/PD: not defined, caution advised
hepatic dosing
- [PO route]
- hepatic impairment: not defined
- [parenteral route]
- hepatic impairment: consider decr. usual dose
Peds Dosing .
- Dosage forms: TAB: 1 mg, 2 mg; SOL: 1 mg per 5 mL; INJ (pre-filled syringe): 0.2 mg per mL; INJ (vial): 0.2 mg per mL
anesthesia adjunct
- [preop, 1-23 mo]
- Dose: 0.004-0.009 mg/kg/dose IM x1; Start: 30-60min before anesthesia; Info: for reduction of secretions
- [preop, 2 yo and older]
- Dose: 0.004 mg/kg/dose IM x1; Start: 30-60min before anesthesia; Info: for reduction of secretions
- [intraop, 1 mo and older]
- Dose: 0.004 mg/kg/dose IV q2-3min prn; Max: 0.1 mg/dose; Info: for reversal of bradycardia, vagal reflexes
neuromuscular blockade reversal adjunct
- [1 mo and older]
- Dose: 0.2 mg IV for each 1 mg neostigmine or 5 mg pyridostigmine dose; Info: for reversal of muscarinic effects of cholinergic agents
sialorrhea, chronic severe
- [3-16 yo]
- Dose: 0.02-0.1 mg/kg/dose PO tid; Start: 0.02 mg/kg/dose PO tid, may incr. 0.02 mg/kg/dose q5-7 days; Max: 0.1 mg/kg/dose tid, 1.5-3 mg/dose; Info: for pts w/ neurologic conditions assoc. w/ problem drooling; give >1h before or 2h after meals
antisialogogue (off-label)
- [PO route, 2 yo and older]
- Dose: 0.04-0.1 mg/kg/dose PO q4-8h prn; Max: 1-2 mg/dose, 8 mg/day; Info: injectable product may be given PO
- [parenteral route, 2 yo and older]
- Dose: 0.004-0.01 mg/kg/dose SC/IM/IV q4-8h prn; Max: 0.1-0.2 mg/dose, 0.8 mg/day
hyperhidrosis (off-label)
- [11 yo and older]
- Dose: 1 mg PO qd-tid prn; Start: 1 mg PO qd; Max: 8 mg/day
renal dosing
- [PO route]
- renal impairment: not defined, caution advised
- HD/PD: not defined, caution advised
- [parenteral route]
- renal failure: consider decr. usual dose
- HD/PD: not defined, caution advised
hepatic dosing
- [PO route]
- hepatic impairment: not defined
- [parenteral route]
- hepatic impairment: consider decr. usual dose