Select a medication above to begin.
Paxil
paroxetine
Black Box Warnings .
Suicidality
antidepressants incr. suicidality risk in peds and young adult pts in short-term studies; monitor closely for clinical worsening and suicidality; advise families and caregivers of need for close observation and communication w/ prescriber; not approved for peds pts
Adult Dosing .
Dosage forms: TAB: 10 mg, 20 mg, 30 mg, 40 mg; SUSP: 10 mg per 5 mL
major depressive disorder
- [20-50 mg PO qam]
- Start: 20 mg PO qam, may incr. by 10 mg/day qwk; Max: 50 mg/day; Info: start 10 mg PO qam, max 40 mg/day in elderly pts; do not crush/chew tab; taper dose gradually to D/C
obsessive-compulsive disorder
- [40 mg PO qam]
- Start: 20 mg PO qam, incr. by 10 mg/day qwk; Max: 60 mg/day; Info: start 10 mg PO qam, max 40 mg/day in elderly pts; do not crush/chew tab; taper dose gradually to D/C
panic disorder
- [40 mg PO qam]
- Start: 10 mg PO qam, incr. by 10 mg/day qwk; Max: 60 mg/day; Info: max 40 mg/day in elderly pts; do not crush/chew tab; taper dose gradually to D/C
social anxiety disorder
- [20 mg PO qam]
- Start: 20 mg PO qam, may incr. by 10 mg/day qwk; Max: 60 mg/day; Info: start 10 mg PO qam, max 40 mg/day in elderly pts; no proven additional benefit at doses >20 mg/day; do not crush/chew tab; taper dose gradually to D/C
generalized anxiety disorder
- [20 mg PO qam]
- Start: 20 mg PO qam, may incr. by 10 mg/day qwk; Max: 50 mg/day; Info: start 10 mg PO qam, max 40 mg/day in elderly pts; no proven additional benefit at doses >20 mg/day; do not crush/chew tab; taper dose gradually to D/C
post-traumatic stress disorder
- [20 mg PO qam]
- Start: 20 mg PO qam, may incr. by 10 mg/day qwk; Max: 50 mg/day; Info: start 10 mg PO qam, max 40 mg/day in elderly pts; no proven additional benefit at doses >20 mg/day; do not crush/chew tab; taper dose gradually to D/C
vasomotor sx, mod-severe menopausal (off-label)
- [10-20 mg PO qd]
- Start: 10 mg PO qd, may incr. to 20 mg PO qd after at least 1wk; Info: do not crush/chew tab; taper dose gradually to D/C
renal dosing
- [adjust dose amount]
- CrCl <30: start 10 mg qd, max 40 mg/day
- HD: decr. usual dose by 50%, max 40 mg/day; no supplement after dialysis; PD: decr. usual dose by 50%, max 40 mg/day; no supplement
hepatic dosing
- [adjust dose amount]
- severe impairment: start 10 mg qd, max 40 mg/day
Peds Dosing .
- Dosage forms: TAB: 10 mg, 20 mg, 30 mg, 40 mg; SUSP: 10 mg per 5 mL
obsessive-compulsive disorder (off-label)
- [7-17 yo]
- Dose: 10-60 mg PO qam; Start: 10 mg PO qam, may incr. by 10 mg/day q1-2wk; Max: 60 mg/day; Info: do not crush/chew tab; taper dose gradually to D/C
social anxiety disorder (off-label)
- [8-17 yo]
- Dose: 10-40 mg PO qam; Start: 10 mg PO qam, may incr. by 10 mg/day q1-2wk; Max: 50 mg/day; Info: do not crush/chew tab; taper dose gradually to D/C
renal dosing
- [not defined]
- renal impairment: consider adult renal dosing for guidance
- HD/PD: consider adult renal dosing for guidance
hepatic dosing
- [not defined]
- hepatic impairment: consider adult hepatic dosing for guidance